BRUTRAX®
Anastrozole 1mg Tablets

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Contact us

Address:
Taj Pharma India Brands
Taj Pharma Group (India)
214, Bake House, Bake House Lane,
Fort, Mumbai 400001, India.

Phone:
+91-22-2637 4592

Toll Free Number:
1800 222 434 or 1800-222-825

FAX:
+91-22-2634-1274

E-mail:
brutrax@tajpharma.com

Full Prescribing Information

USE IN SPECIFIC POPULATIONS

Pregnancy

PREGNANCY CATEGORY X
Anastrozole may cause fetal harm when administered to a pregnant woman and offers no clinical benefit to premenopausal women with breast cancer. Anastrozole is contraindicated in women who are or may become pregnant. In animal studies, anastrozole caused pregnancy failure, increased pregnancy loss, and signs of delayed fetal development. There are no studies of anastrozole use in pregnant women. If anastrozole is used during pregnancy, or if the patient becomes pregnant while receiving this drug, the patient should be apprised of the potential hazard to the fetus and potential risk for pregnancy loss.

Nursing Mothers

It is not known if anastrozole is excreted in human milk. Because many drugs are excreted in human milk and because of the tumorigenicity shown for anastrozole in animal studies, or the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

Pediatric Use

Clinical studies in pediatric patients included a placebo-controlled trial in pubertal boys of adolescent age with gynecomastia and a single-arm trial in girls with McCune-Albright Syndrome and progressive precocious puberty. The efficacy of anastrozole in the treatment of pubertal gynecomastia in adolescent boys and in the treatment of precocious puberty in girls with McCune-Albright Syndrome has not been demonstrated.

  1. McCune-Albright Syndrome Study
  2. Pharmacokinetics in Pediatric Patientsy

Geriatric Use

The pharmacokinetics of anastrozole is not affected by age.

Renal Impairment

Since only about 10% of anastrozole is excreted unchanged in the urine, the renal impairment does not influence the total body clearance. Dosage adjustment in patients with renal impairment is not necessary.

Hepatic Impairment

TThe plasma anastrozole concentrations in the subjects with hepatic cirrhosis were within the range of concentrations seen in normal subjects across all clinical trials. Therefore, dosage adjustment is also not necessary in patients with stable hepatic cirrhosis. Anastrozole has not been studied in patients with severe hepatic impairment .


VISION

At Taj Pharmaceuticals our goal is to create innovative drugs and diagnostic tools for the medicine of tomorrow. Rapid progress in the sciences is providing crucial insights into the underlying molecular mechanisms of disease, opening up new ways for prevention, diagnosis and therapy. With the expertise in Diagnostics and Pharmaceuticals, Taj Pharmaceuticals is best placed to capture the value from the Healthcare Revolution.

The future will be shaped by fundamental paradigm shifts ushering in a new era of more effective medicine. Diagnosis, prevention and treatment will be linked more closely than ever before in integrated strategies offering patients and healthcare providers highly focused, individualised care. We are confident that, with our outstanding workforce, cutting-edge science and state-of-the-art technology base, we can meet tomorrow's needs for integrated healthcare solutions.

MISSION

As one of the world's leading innovation-driven healthcare groups, whose core businesses are Pharmaceuticals and Diagnostics, Taj Pharmaceuticals aims to supply products and services that significantly improve people's lives by helping to prevent, diagnose and treat disease.

Taj Pharmaceuticals is committed to a system of corporate governance that conforms to the latest standards and takes due account of our corporate development. The safety and health of our employees and the public, as well as the protection of our neighbourhoods and the environment, have high priority at all Group facilities. In all we do, we are guided by the principle of sustainable development.

Download Brutrax Overview

Brutrax® (Aastrozole Tablet) may help reduce your risk of breast cancer recurrence sold by Taj Pharmaceuticals Limited (India), a global pharmaceuticals company. It is available in India, Middle East and a few other South Asian countries.

Patient Counseling Information PDF
Full Prescribing Information PDF

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Note: This product information is intended only for residents of the India. Taj Pharmaceuticals Limited, medicines help to treat and prevent a range of conditions—from the most common to the most challenging—for people around the world. The Price of the drugs indicated above may not match the actual price at which they are sold. Prices can change depending on many factors, including local taxes. These are only approximate indicative prices of the drug. The products discussed herein may have different product labelling in different countries. The product information provided in this site is intended only for the residents of India.

Information for Health Care Professionals
*** Please consult local Prescribing Information for any product before use. This website is an international information resource for healthcare professionals with an interest in disease management. This website is not intended to replace the advice of a qualified healthcare professional. Above brand is a trademark of the Taj group of companies (Taj Pharmaceuticals Limited).

About BRUTRAX® (anastrozole 1mg Tablets)

BRUTRAX® is a prescription medicine used in women after menopause (“the change of life”) for: treatment of early breast cancer, after surgery, in women whose breast cancer is hormone receptor-positive, the first treatment of breast cancer that has spread to nearby tissue or lymph nodes (locally advanced) or has spread to other parts of the body (metastatic), in women whose breast cancer is hormone receptor-positive or the hormone receptors are not known. Treatment of advanced breast cancer, if the cancer has grown, or the disease has spread after tamoxifen therapy BRUTRAX® (anastrozole) does not work in women with breast cancer who have not gone through menopause (premenopausal women). BRUTRAX® (anastrozole) is used with other treatments, such as surgery or radiation, to treat early breast cancer in women who have experienced menopause (change of life; end of monthly menstrual periods). This medication is also used in women, who have experienced menopause, as a first treatment of breast cancer that has spread within the breast or to other areas of the body. This medication is also used to treat breast cancer in women whose breast cancer has worsened after taking tamoxifen. BRUTRAX® (anastrozole) is in a class of medications called nonsteroidal aromatase inhibitors. It works by decreasing the amount of estrogen the body makes. This can slow or stop the growth of many types of breast cancer cells that need estrogen to grow.

About Taj Pharma Group

Taj Pharma is one of the leading generic and branded pharmaceutical manufacturing company in India. We hold top positions in different established markets worldwide and are building a strong presence in many emerging generics markets. We have eight manufacturing sites in India to support our market standing, holding a strong regulatory position and major certifications for most markets. Today, we market more than 500 branded and 4600 generics compositions to consumers in more than 40 countries and territories across the globe. Our products cover a vast array of therapeutic categories, and we offer an extensive range of dosage forms and delivery systems including oral solids, controlled-release, steriles, injectables, topicals, liquids, transdermals, semi-solids and high-potency products.

© Copyright 2019 Taj Pharmaceuticals Limited. All rights reserved.Taj Pharma Group India.
Brutrax® is Registered Trade Mark of Taj Pharma India 2009-2019

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